A multimodal method of ache management may possibly optimize the remedy of Serious ache, along with support Together with the thriving tapering with the opioid analgesic (see WARNINGS, Withdrawal and DRUG ABUSE AND DEPENDENCE).
Inform people that leaving acetaminophen and codeine phosphate tablets unsecured can pose a fatal possibility to others in the home.
The administration of acetaminophen and codeine phosphate tablets or other opioids may obscure the prognosis or clinical program in people with acute abdominal circumstances.
Acquire this medication by mouth as directed by your physician. You might acquire this drug with or devoid of food stuff. Should you have nausea, it could assistance to acquire this drug with foods.
noticing your suffering acquiring worse. In case your pain receives worse after you consider acetaminophen and codeine phosphate tablets, do not choose extra of acetaminophen and codeine phosphate tablets with no very first speaking with your healthcare service provider.
Rapid discontinuation has also been connected with attempts to seek out other resources of opioid analgesics, which get more info may be baffled with drug-trying to get for click here abuse.
Monitor for respiratory despair, especially all through initiation and next any rise in dose; close monitoring will be essential in patients at enhanced threat and/or People getting concomitant drugs that boost the danger of respiratory melancholy
Codeine sulfate was not mutagenic during the in vitro bacterial reverse mutation assay or clastogenic during the in vitro Chinese hamster ovary cell chromosome aberration assay.
Acute or severe bronchial asthma, in an unmonitored location or within the absence of resuscitative products
The exact system of your analgesic Qualities of acetaminophen is not proven but is assumed to involve central actions.
Females of child bearing possible ought to understand that prolonged use for the duration of pregnancy may result in neonatal opioid withdrawal syndrome Which prompt recognition and treatment will be necessary.
Use with caution; get started with reduced doses or with lengthier dosing intervals and titrate slowly though diligently checking for Unwanted side effects.
So that you can stay away from establishing get more info withdrawal indications, instruct patients not to discontinue acetaminophen and codeine phosphate tablets with no initially discussing a tapering program While using the prescriber (see DOSAGE AND ADMINISTRATION).
Avoid using acetaminophen and codeine phosphate tablets in adolescents twelve to 18 years of age who produce other here danger things which could raise their sensitivity for the respiratory depressant consequences of codeine here Except if the benefits outweigh the challenges.